A major city, the capital of Italy and the Italian region of Lazio, located on the Tiber River; the ancient capital of the Roman Empire. • A metropolitan city of Lazio, Italy. • The Italian government. • An ancient empire based out of the city of Rome, covering vast territories in Europe, Asia and Africa; in full, Roman Empire. • The Holy See, the leadership of the Roman Catholic Church, particularly prior to the establishment of the Vatican City in the 19th century. • The Church of Rome, the Roman Catholic Church generally. • A number of places in the United States: • An unincorporated community in Covington County, Alabama. • A city, the county seat of Floyd County, Georgia. • A census-designated place in Peoria County, Illinois. • An unincorporated community in Perry County, Indiana. • A village in Henry County, Iowa. • A ghost town in Ellis County, Kansas. • An unincorporated community in Sumner County, Kansas. • An unincorporated community in Daviess County, Kentucky. • A town in Kennebec County, Maine. • An unincorporated community in Sunflower County, Mississippi. • An unincorporated community in Douglas County, Missouri. • A city in Oneida County, New York. • A village in Green Township, Adams County, Ohio. • An unincorporated community in Delaware County, Ohio. • A ghost town in Morrow County, Ohio. • An unincorporated community in Richland County, Ohio. • An unincorporated community in Malheur County, Oregon. • A borough in Bradford County, Pennsylvania. • An unincorporated community in Smith County, Tennessee. • A town and unincorporated community in Adams County, Wisconsin. • A census-designated place in Jefferson County, Wisconsin. • A number of townships, including in Illinois, Iowa, Michigan, Minnesota, Ohio (3) and Pennsylvania (2), listed under Rome Township. • A surname.