America; the United States; an appellation given in honor of Christopher Columbus. • A female personification of the United States. • A river in British Columbia, Canada and in Washington and Oregon, United States, flowing from the Canadian Rockies to the Pacific Ocean. • District of Columbia. The federal capital region of the United States of America, including Washington, D.C. • Several places in the United States. • The capital city of South Carolina, and the county seat of Richland County. • A town in Houston County, Alabama. • A neighborhood of San Diego, California. • A census-designated place in Tuolumne County, California. • A town in Tolland County, Connecticut. • A city in Monroe County, Illinois. • An unincorporated community in Fayette County, Indiana. • An unincorporated community in Marion County, Iowa. • A city, the county seat of Adair County, Kentucky. • A town, the parish seat of Caldwell Parish, Louisiana. • A town in Washington County, Maine. • A census-designated place and planned community in Howard County, Maryland. • A city, the county seat of Marion County, Mississippi, named for the city in South Carolina. • A city, the county seat of Boone County, Missouri. • A town in Coos County, New Hampshire. • A census-designated place in Warren County, New Jersey. • A town in Herkimer County, New York. • A town, the county seat of Tyrrell County, North Carolina. • An unincorporated community in Tuscarawas County, Ohio. • An unincorporated community in Williams County, Ohio. • A borough of Lancaster County, Pennsylvania. • A city in Brown County, South Dakota. • A city, the county seat of Maury County, Tennessee. • An unincorporated community in Fluvanna County, Virginia. • An unincorporated community in Fayette County, West Virginia. • An unincorporated community in Clark County, Wisconsin. • A number of townships, listed under Columbia Township. • Columbia University. • Columbia Pictures, a major American film production corporation • Space Shuttle Columbia, named after the Columbia Rediviva ship. • A supercontinent thought to have existed in the Paleoproterozoic. • A rural locality in northeast Queensland, Australia. • Obsolete form of Colombia.